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Three-dimensional cartilage tissue engineering using placenta-derived extra-embryonic mesenchymal stem cells: From isolation to differentiation
12/12/2025
Biomedicines, 18/09/2025 Introduction Mesenchymal stem cells (MSCs) offer promising prospects for novel treatment modalities in cellular therapies and artificial organ production, due to their remarkable
Safety assessment of multiple systemic administration of human mesenchymal stem cell-conditioned medium for various chronic diseases
11/12/2025
PLoS One, 06/05/2025 Introduction Inflammation is an essential protective response of the body aimed at combating infectious agents and tissue damage [1]. However, the inflammatory
Exosomes and hair regeneration: A systematic review of clinical evidence across alopecia types and exosome sources
25/11/2025
Clinical, Cosmetic and Investigational Dermatology, 28/08/2025 Introduction Hair loss disorders such as androgenetic alopecia (AGA) and other non-scarring alopecias are a significant cosmetic and psychologic
Placenta-Derived Mesenchymal Stem Cells (pMSCs) Reverse Diabetes-Associated Endothelial Complications in a Preclinical Animal Model
21/11/2025
International Journal of Molecular Sciences, 20/08/2025 Background Despite remarkable advancements in medical science, diabetes, particularly type 1 diabetes (T1D), continues to pose significant health challenges.
High-activity placenta-derived mesenchymal stem cells combined with low-intensity extracorporeal shock wave therapy for diabetic erectile dysfunction: a prospective randomized controlled trial
18/11/2025
Stem Cell Reasrch & Therapy, 09/07/2025 Background Erectile dysfunction (ED) is a common condition in which men are unable to achieve or maintain an erection
Secretome from human placenta-derived mesenchymal stem cells repairs mechanically induced meniscus injury in mice by activating the proliferation and suppressing the apoptosis of endogenous meniscus progenitor cells
14/11/2025
Stem Cell Reasrch & Therapy, 14/10/2025 Background Meniscus injury (MI) is a common condition, particularly affecting athletes and active individuals. While meniscectomy is the primary
Effectiveness and safety of multiple injections of human placenta-derived MSCs for knee osteoarthritis: a nonrandomized phase I trial
11/11/2025
BMC Musculoskelet Disord, 26/04/2025 Introduction Osteoarthritis (OA) is a common degenerative joint disease characterized by cartilage degradation and subchondral bone abnormalities, leading to reduced quality
Injection of human umbilical cord mesenchymal stem cells exosomes for the treatment of knee osteoarthritis: from preclinical to clinical research
07/11/2025
Journal of Translational Medicine, 11/06/2025 Introduction Knee osteoarthritis (OA) is the most common chronic joint disease, causing damage to cartilage, subchondral bone, and the synovial
Human umbilical cord mesenchymal stem cell therapy for atopic dermatitis through inhibition of neutrophil chemotaxis
04/11/2025
Stem Cell Research & Therapy, 14/05/2025 Background Atopic dermatitis (AD) is a chronic inflammatory skin condition, often described as an “immortal cancer” owing to its
Exosome Therapy for Chronic Wound Healing
31/10/2025
Plastic & Reconstructive Surgery – Global Open, 17/10/2025 Introduction Chronic wounds, particularly those associated with diabetes, venous insufficiency, and smoking, present a persistent healthcare challenge
