Stem Cells: Anti-Aging Treatment Breakthrough in 2023?

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In the pursuit of combating aging, stem cell therapies have emerged as a groundbreaking approach, offering the potential to rejuvenate the body at a cellular level. This article delves into how stem cell treatments, alongside anti-aging genes, can significantly slow down aging and enhance overall health and lifespan.

DVCSTEM, November 23 , 2023

Anti-aging effects of stem cells

Our current knowledge of human stem cells makes it feasible to delay aging and improve health and lifespan. Stem cell treatments can play a crucial role in delaying the aging process. Together with anti-aging genes, a stem cell infusion can create a sophisticated shield that can prevent or slow the effects of aging.

Increased wear and tear of the body’s natural stem cells increases cellular damage and accelerates the natural aging process. Stem cell therapy combined with anti-aging genes can potentially absorb the process of cellular aging.

Regenerative stem cell therapy rejuvenates existing cell types

Introducing “youthful” human stem cells into the body can rejuvenate existing cells and allow the body to age more gracefully & even reverse some effects of the aging process.

‍As we age, our cells get sick and die. When a cell dies, it creates a cascade of events, leading to inflammation and disease that can decrease the human lifespan. There are several ways in which stem cells may be able to delay aging, including:

  1. Regenerating damaged tissue: Stem cells can differentiate into various cell types and can be used to replace damaged tissue, potentially reversing the effects of aging.
  2. Enhancing repair mechanisms:Stem cells can stimulate the production of growth factors and other signaling molecules that can enhance the body’s repair mechanisms, helping to maintain healthy tissue and delay the onset of age-related changes.
  3. Modulating the immune system:Stem cells may have immune-modulatory effects, which could help to maintain a healthy immune system and delay the onset of age-related immune dysfunction.
  4. Reducing inflammation:Some studies have suggested that stem cells may have anti-inflammatory effects, which could help reduce the chronic low-grade inflammation associated with aging.
  5. Protecting against oxidative stress:Stem cells may be able to protect against oxidative stress, which is a process that can lead to cell damage and is thought to play a role in aging

The benefits of stem cell therapies for aging

  • A feeling of vitality and rejuvenation
  • Improved capacity for physical activities
  • Thickening and improved quality of hair
  • Increased libido
  • A decrease in pain
  • Increased strength, balance & overall mobility
  • Enhanced immunity
  • Overall improvement in the quality of life
  • Immune system regulation

Stem cell research surrounding aging

It is important to note that stem cell research is an active area of study, and more research is needed to understand the potential of stem cells to delay aging entirely.

Many environmental factors accelerate aging, such as stress, pollution, lifestyle, injuries, disease, and exposure to toxins. A recently published study reviewed the evidence that delaying and reversing aging in cells is feasible.

Epigenetic (non-genetic influences on gene expression) changes drive aging, and reversing these changes extends lifespan. (1) Epigenetic control of gene expression occurs by chemical modification of DNA. Aging can be delayed by choosing an active lifestyle and decreasing harmful environmental factors.

What are mesenchymal stem cells?

MSCs are adult stem cells that have self-renewal, immunomodulatory, anti-inflammatory, signaling, cell division, and differentiation properties. MSCs self-renewal capacity is characterized by their ability to divide and develop into multiple specialized cell types in a specific tissue or organ.

MSCs may become unique stem cell types and create more stem cells when placed in cell culture and undergo Vitro fertilization.  (Vitro fertilization can help grow stem cells in a laboratory setting.   MSCs can also replace cells that are damaged or diseased.  MSCs can be sourced from a variety of tissue, including adipose tissue (fat), bone marrow, umbilical cord tissue, blood, liver, dental pulp, and skin.

Clinical trials and MSCs

MSCs are widely used in treating various diseases due to their self-renewable, differentiation, anti-inflammatory, and immunomodulatory properties. In-vitro (performed in a laboratory setting) and in-vivo (taking place in a living organism) studies have supported an understanding of the mechanisms, safety, and efficacy of MSC therapy in clinical applications. (3)

According to a recent study conducted by Biehl et al., “The two defining characteristics of a stem cell are perpetual self-renewal and the ability to differentiate into a specialized adult cell type.” (1)

How stem cell therapy reduces inflammation at a cellular level

Stem cells can influence the processes of white blood cells. A macrophage is a large white blood cell that is an integral part of our immune system. Macrophages are a type of blood cell that removes infectious agents and dead cells from the blood that can create inflammation (M1) and reduce inflammation (M2).

M1 macrophages are associated with accelerated aging, and M2 macrophages are associated with anti-aging. Mesenchymal stem cells shift M1 macrophages to M2. They are, therefore, giving the human body more tools to combat the natural aging process by significantly reducing inflammation.

Stem cells can maintain mitochondrial health

stem cell can also maintain mitochondrial health (the powerhouse of the cell) by intercellular communication through tunneling nanotubes. This system senses the mitochondrial status of the patient’s cells and physically transfers mitochondria from stem cells to unhealthy cells.

Stem cell anti-aging, how our cells age

Aging is a complex, natural process; the effect of environmental factors, genetics, and routine wear and tear on the body eventually takes a toll in many ways. It is this result of living life that can bring unavoidable health problems. Over time, the cells of the body age as we do, resulting in their inability to replicate; they become damaged and die. The loss of efficient cell replication is what causes our bodies to age.

Anti aging treatment

Stem cells are a promising potential solution for reversing the visible signs of aging. These special cells have the ability to regenerate damaged tissues and improve overall cellular function, which may lead to a reduction in the appearance of wrinkles and other age-related changes.

Some studies have suggested that stem cells may have anti-aging effects on the skin by increasing the production of collagen, a protein that gives skin its elasticity and strength.
While more research is needed to fully understand the potential of stem cells for anti-aging treatments, the early results are promising and suggest that stem cells may play a key role in the development of effective anti-aging therapies in the future.

What are the 10 signs of aging?

Some of the most common signs of aging are:

  • Impaired vision
  • Impaired hearing
  • Loss of strength in muscles
  • Loss of bone density
  • Decreased immune system function
  • Decreased cognitive ability
  • Less efficient metabolism.
  • Loss of energy
  • Hair loss
  • Decreased balance and overall mobility

Reversing Aging

Stem cells are a type of cell that has the ability to develop into any type of cell in the body. They are able to divide and replicate indefinitely, making them a potential solution for reversing the aging process. Studies have shown that stem cells can regenerate damaged tissues, reduce inflammation, and improve overall cellular function, which may lead to a reduction in the visible signs of aging.

Additionally, stem cells have the ability to modulate the immune system, which may help to improve overall health and well-being as we age. While more research is needed to fully understand the potential of stem cells for reversing aging, the early results are promising and suggest that stem cells may play a key role in the fight against aging.

So can stem cells reverse ageing?

  1. A study published in the journal Aging Cell found that bone marrow stem cells, can improve the function of aged immune cells and increase the lifespan of mice. The study suggests that bone marrow stem cells may have anti-aging effects by reducing inflammation and improving immune function.
  2. A review published in the Journal of Aging Research & Clinical Practice analyzed the results of several studies on the use of stem cells for the treatment of age-related diseases. The review found that stem cells have the potential to regenerate damaged tissues, improve organ function, and reduce the risk of age-related diseases.
  3. A study published in the journal Stem Cells Translational Medicine found that stem cells can improve skin health and reduce the appearance of wrinkles in mice. The study suggests that stem cells may have anti-aging effects on the skin by increasing the production of collagen, a protein that gives skin its elasticity and strength.

While these studies are promising, it’s important to note that more research is needed to fully understand the potential of stem cells for reversing aging. It’s also important to note that stem cells are not a magic bullet and their use should be approached with caution and under the guidance of a qualified medical professional.

‍Stem cell therapy for anti-aging

Aging cells can contribute to disease. Thus if cell aging can be prevented, slowed down, or even reversed, many diseases could be better managed. Stem cells may be able to slow this process down & combat certain age-related conditions.

How do stem cells slow the aging process?

With stem cell therapies, you are replenishing the supply of stem cells to allow the body to repair and rejuvenate all the organs of your body.

Stem cells possess unique factors that aid in anti-aging by helping our bodies regenerate cellular tissues, such as:

  • Skin
  • Joints
  • Bones
  • Organs

This advanced therapy may be able to repair tissue that has been damaged by stress, injury, and environmental factors.

Can stem cells cure aging?

With our current knowledge of stem cells, it is technically feasible to delay aging and improve both health and lifespan. Stem cells can play a crucial role in delaying the aging process. Stem cells, in combination with anti-aging genes, can create a sophisticated shield, which can prevent the effects of aging.

The potential benefits of stem cells as an anti-aging therapy include cell rejuvenation, improved organ function, and reduced risk of age-related diseases. While more research is needed to fully understand the potential of stem cells for reversing aging, the early results are promising.

Reference

(1) Rožman, P. (2019, July 19). How Could We Slow or Reverse the Human Aging Process and Extend the Healthy Life Span with Heterochronous Autologous cells Hematopoietic Stem Cell Transplantation. Retrieved from     https://www.ncbi.nlm.nih.gov/pubmed/31203790

(2) Ageyn (2022, Dec) Exploring the Science Behind the Aging Process in 2023 https://www.ageyn.com/post/what-is-aging

(3) Watt, Fiona M, and Ryan R Driskell. “The Therapeutic Potential of Stem Cells.” Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, The Royal Society, 12 Jan. 2010, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842697/.

(4) Mao, Fei, et al. “Mesenchymal Stem Cells and Their Therapeutic Applications in Inflammatory Bowel Disease.” Oncotarget, Impact Journals LLC, 6 June 2017, https://www.ncbi.nlm.nih.gov/pubmed/28402942.

(5) Walker, J. T., Keating, A., & Davies, J. E. (2020, May 28). Stem Cells: Umbilical Cord/Wharton’s Jelly Derived. Cell Engineering and Regeneration. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992171/.

(6) Torres Crigna, A., Daniele, C., Gamez, C., Medina Balbuena, S., Pastene, D. O., Nardozi, D., … Bieback, K. (2018, June 15). Stem/Stromal Cells for Treatment of Kidney Injuries With Focus on Preclinical Models. Frontiers in medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013716/.

Source: DVCSTEM

Link: https://www.dvcstem.com/post/anti-aging-stem-cells

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